New York City, 1922. Nicolás Caraveo, a 17-year-old transgender boy from Wisconsin, has no interest in the city's glamor. Going to New York is all about establishing himself as a young professional, which could set up his future--and his life as a man--and benefit his family.
Nick rents a small house in West Egg from his 18-year-old cousin, Daisy Fabrega, who lives in fashionable East Egg near her wealthy fiancé, Tom--and Nick is shocked to find that his cousin now goes by Daisy Fay, has erased all signs of her Latine heritage, and now passes seamlessly as white.
Nick's neighbor in West Egg is a mysterious young man named Jay Gatsby, whose castle-like mansion is the stage for parties so extravagant that they both dazzle and terrify Nick. At one of these parties, Nick learns that the spectacle is all meant to impress a girl from Jay's past--Daisy. And he learns something else: Jay is also transgender.
As Nick is pulled deeper into the glittery culture of decadence, he spends more time with Jay, aiming to help his new friend reconnect with his lost love. But Nick's feelings grow more complicated when he finds himself falling hard for Jay's openness, idealism, and unfounded faith in the American Dream.